Lactobacillus rhamnosus GG (LGG®) is one of the most extensively studied probiotic strains with over 1,000 scientific publications. It survives stomach acid and bile, adheres strongly to intestinal mucosa, and produces antimicrobial substances. It helps restore gut flora after antibiotics, reduces duration of infectious diarrhea, alleviates IBS symptoms, prevents antibiotic-associated diarrhea, and modulates immune response (reduces risk of atopic dermatitis, respiratory infections). Each sachet delivers 10 billion CFU in a convenient, stable powder form.
Lactobacillus rhamnosus GG (ATCC 53103) is a Gram-positive, facultative anaerobic bacterium originally isolated from human intestinal flora.
Key characteristics:
1. Acid and bile tolerance: Survives passage through the stomach (pH 2.5) and small intestine, reaching the colon in high numbers.
2. Adhesion to mucus: Produces pili that bind strongly to intestinal epithelial cells, prolonging colonization (up to 1–3 weeks after discontinuation).
3. Antimicrobial production: Secretes bacteriocins (e.g., LGG-derived bacteriocin) and short-chain fatty acids that inhibit pathogens like Clostridium difficile, Salmonella, and E. coli.
4. Immune modulation: Enhances IgA production, increases regulatory T cells, and reduces pro-inflammatory cytokines (IL-6, TNF-α).
Evidence-based uses: Meta-analyses confirm LGG reduces risk of antibiotic-associated diarrhea by 50-60%, shortens acute diarrhea duration by 1 day, and lowers incidence of atopic dermatitis by 30% in high-risk infants.
| Probiotic Strain | Lactobacillus rhamnosus GG (LGG®) – 10 billion CFU per sachet (at time of manufacture) |
|---|---|
| Excipients | Maltodextrin (carrier), silicon dioxide (anti-caking agent), ascorbic acid (antioxidant). |
| Allergen Information | Free from gluten, dairy, soy, eggs, nuts, and artificial colors. Suitable for vegetarians. |
Infants (6 months – 2 years): ½ sachet (5 billion CFU) once daily, mixed with breast milk, formula, or water.
Children (2–12 years): 1 sachet (10 billion CFU) once daily.
Adults (≥12 years): 1–2 sachets once daily.
Antibiotic-associated diarrhea prevention: Start on first day of antibiotics, continue for 1 week after completion.
Acute diarrhea: 2 sachets daily for 5–7 days.
Tear open the sachet and mix the powder with cold or lukewarm water, milk, juice, or soft food (yogurt, applesauce). Do not mix with hot liquids (above 40°C) as heat kills probiotics. Consume immediately after mixing. For infants, mix with expressed breast milk or formula at room temperature.
| Dosage Form | Powder for oral suspension in stick sachet |
|---|---|
| Net weight per sachet | 1 gram |
| Packaging | 10 sachets per laminated foil pack, 10 packs per carton (100 sachets/carton) |
| Manufacturing Standard | WHO-GMP, ISO 22000, HACCP |
| Shelf Life | 24 months from date of manufacture (unopened) | Country of Origin | India |
| Minimum Order Qty | 1000 sachets (100 packs of 10 sachets) |
LGG is generally recognized as safe (GRAS). Rare mild side effects may include:
Store below 25°C (77°F) in a cool, dry place. Do not freeze. Avoid direct sunlight.
Keep sachets in original pack until use. Do not transfer to other containers. High humidity may reduce potency.
Full export docs: COA, Stability data, GMP certificate, FSC, MSDS, commercial invoice. Ambient shipping, protect from heat.
